I found this article about the role of epigenetic changes in premature aging disorders. Werner syndrome and Hutinson-Gilford Progeria are genetic disorders which had not been associated with a genetic cause until recently. Scientists in Spain studied the genetic profiles of WS and HGP patients and just discovered that DNA methylation patterns may have an impact on premature aging disorders. DNA methylation patterns change with age, so certain methylation landscapes may be responsible for the phenotypic changes and susceptibility to certain diseases that accompany age-related processes.
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