And 3rd generation sequencing (includes helpful illustrations of new techniques)
Tuesday, June 29, 2010
Monday, June 28, 2010
The pattern of genetic diversity in malaria (2 genes) matches human migration out of Africa, contracting the suggestion that the 1st human malaria infections coincided with the origins of agriculture. Science tidbit on Current Biology paper here.
Here is an interesting Research Highlight on the relationship between gene copy number and protein production, and how this varies among genes -- sometimes there is a clear dosage effect, sometimes not... interesting to look at in terms of history of whole genome duplication (WGD), which has happened twice in vertebrate evolution....
Friday, June 25, 2010
Interesting article in Nature on academic career satisfaction and salaries, with comparisons between men and women across regions. An especially interesting graph demonstrating why all women should read "Women Don't Ask" before negotiating a new job offer...
The Sanger center is now doing a (UK) 10,000 genomes projects -- about half of these will be exomes of people with "extreme phenotypes" (obesity, autism, heart disease...). The other half will be full genomes (so should include indels, copy variation) of family pairs/twins in on-going longitudinal studies.
Wednesday, June 16, 2010
we do use phylogenies (!) to examine:
1) lemur ecology and evolution
2) mammal longevity
Sunday, June 13, 2010
Friday, June 11, 2010
New paper in Science suggests that oxytocin promotes altruism within groups, but aggression toward out-group competitors -- a "tend and defend" response. Includes a commentary by Greg Miller.