Tuesday, October 4, 2011
Misfolded human tRNA isodecoder binds and neutralizes a 3′ UTR-embedded Alu element
The authors of this article demonstrate how two kinds of RNA, tRNA and Alu RNA, interact. tRNA binds to Alu RNA, causing a rearrangement of 3' UTR. Because of the large number of Alu elements and diversity of tRNAs in humans, they propose that this is a posttranscriptional regulation mechanism that might be unique to primates.
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