In the current issue of Science
Bushdid et al. find that humans are able to discriminate at least 1 trillion
olfactory stimuli. This finding far exceeds the previous estimates that humans can
detect only 10,000 different odors. The authors used combinations of 128
odorous molecules to determine how many unique stimuli exist. They performed
tests with human subjects to determine the discriminability of mixtures that
varied in the percentage of odor components and from there applied a
theoretical framework to determine the number of unique olfactory stimuli. They
found a large discrepancy between the abilities of subjects to discriminate
different mixtures, and they believe their estimate of 1 trillion
distinguishable olfactory stimuli to be a conservative one.
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