Thursday, October 31, 2013

New method for determining Identity by Descent

This article describes a method for determining Identity by Descent using sequencing data instead of SNP array data.  The method targets specific known IBD segments and calculates a genotype error rate for that segment.  Genotype error rate is calculated using a ratio of the observed rate and expected rate of homozygotes or heterozygotes.
http://www.cell.com/AJHG/abstract/S0002-9297(13)00454-0

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