Tuesday, November 2, 2010

1000 Genomes Project


The first major paper from the project was published last week in Nature.

So now we supposed have 94% of human variable sites documented -- including the identification of many 'rare variants'.

An interest snippet from the Nature News article:
"results of the survey revealed, with each person's genome carrying some 250 or 300 so-called 'loss-of-function' mutations that incapacitate the gene in which they occur.

"That's quite a lot — it's on the order of 1% of all genes," says Richard Durbin, a genomicist at the Wellcome Trust Sanger Institute in Hinxton, UK, and one of the chief architects of the project."

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