New directed gene therapy -- CCR5 disruption in humans

"A gene-therapy method that specifically disrupts a single gene may have had its first success in the clinic, potentially boosting immune-cell counts in a small number of patients with HIV."

Twin studies - new role

Nice review paper on twin studies of epigenetics in recent TIG:

"We describe how large-scale epigenetic studies of twins can improve our understand- ing of how genetic, environmental and stochastic factors impact upon epigenetics, and how such studies can provide a comprehensive understanding of how epige- netic variation affects complex traits."

16th Summer Institute in Statistical Genetics

It's a bit pricey but probably a great workshop for stats and/or genetics geeks. Joe Felsenstein and Sudhir Kumar are among the instructors.

Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

Researchers sort out the mechanism for only methylating hemimethylated CpG sites and therefore avoiding de novo methylation.

The Developmental Role of Agouti in Color Pattern Evolution

Genomic signatures of diet-related shifts during human origins

Review of genomic evidence for dietary shifts in humans

Gene clustering pattern, promoter architecture, and gene expression stability in eukaryotic genomes