Hunter-gatherer genomic diversity suggests a southern African origin for modern humans

Contrary to previous studies of genetic diversity in Africa, this study claims that the modern human origins can be traced to Southern Africa. The authors analyzed genome-wide SNPs of hunter gatherers (Hazda, Khoisan, etc.)and 21 other African populations. They found that the best fit model using linkage disequilibrium for location of origin is in southwestern Africa. This is a surprising results, as most other reviews of genetic diversity would place this origin in Eastern Africa.

Identifying CNV Hotspots

Flanking SNPs inform CNV mutation rates.

Detecting gene-gene interactions in genome-wide studies

A new method to analyze SNPs and identify gene-gene interactions in genome-wide case-control studies. It has a catchy name - “BOolean Operation-based Screening and Testing” (BOOST). This paper is mathematically technical, but worth skimming.